Which best describes the effects when alcohol and other drugs such as cannabis are consumed together?

★ Q: Which best describes the effects when alcohol and other drugs such as cannabis are consumed together?
Which best describes the effects when alcohol and other dream drugs such as cannabis are consumed together
Which best describes the effects when alcohol and other drugs are consumed together?
  the combined effects are predictable
  the effects of the drugs are lessened by the effects of the alcohol
  the effects of the alcohol are lessened by the effects of the drugs
  the combined effects increase the risk of accidental injury and other tragic consequences

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the combined effects increase the risk of accidental injury and other tragic consequences