When are licensees and staff obligated to protect patrons from harm related to drinking?

Question: When are licensees and staff obligated to protect patrons from harm related to drinking?
  when the patrons are on the premises
  when the patrons have left the premises
  when the patrons are both on and off the premises
  when the patrons are on the premises during regular business hours

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when the patrons are both on and off the premises